Today 2 Jobs

Sr Associate Scientist – Attribute Sciences

December 26, 2014

NOTE: This job listing has expired and may no longer be relevant!

9b18c392fcadc8f3fbf7bd7293eeee42
Job Description
 
Scientific leadership of analytical and biochemical characterization activities for biotherapeutic protein commercialization, including: assay development, planning and execution in support of process characterization, product characterization, regulatory filing, response to regulatory questions and process/analytical investigations. Specific activities will include characterizing process influence on protein primary structure in drug substance and drug product, as well as characterizing stability against degradation product formation during storage. Develop and apply characterization strategies to drug substance and drug product comparability studies, characterization of product degradation pathways, and reference standard characterization. In addition, there will be a focus on developing technologies to reduce cost of quality, including impureomics / proteomics technologies, implementation of mass spectrometry in QC, and multi-attribute protein mass spectrometry methods. This position will also emphasize mass spectrometric method development and application for product characterization, including primary structure / glycan structure elucidation, determination of product purity profiles, product attribute criticality and target product profiles, process characterization and product testing. Generation of technical documents and technical presentations is required as well as assistance in the preparation of relevant sections of regulatory documents. Additional responsibilities include keeping current with field of expertise, including literature and technology development. This position is also responsible for providing scientific results that support the generation of publications, patents and regulatory submissions, participating in recruiting and candidate evaluation, and monitoring and analyzing competitive scientific knowledge from external sources. 

Basic Qualifications 
Master’s degree & 3 years of scientific experience 
OR 
Bachelor’s degree & 5 years of scientific experience 

Preferred Qualifications 
– Master’s degree in biological sciences, biochemistry, pharmaceutical sciences, physical sciences, chemical engineering 
– Expertise with mass spectrometry of proteins, peptides and glycans. 
– Expertise with statistical software is recommended 
– 7 years of scientific experience within the biotech industry, experience to include data analyses, statistical analysis, setting acceptance criteria in support of process development, process/method transfers, and comparability studies. 
– Good problem solving skills requiring the application of scientific theory 
– Ability to demonstrate skills in independently determining and developing scientific analysis and solutions, as well as demonstrate strong laboratory work skills to include the design and performance of scientific experiments and interpretation of results. 
– Troubleshooting skills 
Demonstrated ability to work collaboratively with other scientists on multidisciplinary teams. 

How to Apply

Apply for this job

Apply for this Job

Paste your AdWords Remarketing code here